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Article information
2012 , Volume 17, ¹ 6, p.47-63
Voropaeva O.F., Shokin Y.I.
Numerical simulation of feedback p53 - Mdm2 in biological process of apoptosis
We have carried out numerical analysis of solutions of 2D nonlinear mathematical model of the interaction of proteins p53 and Mdm2, which play a key role in the biological process of apoptosis.
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Keywords: apoptosis,tumor necrosis factor, delay differential equation, numerical simulation, Andronov-Hopf bifurcation
Author(s):
Voropaeva Olga Falaleevna
Dr.
Position: Leading research officer
Office: Federal Research Centerfor Information and Computational Technologies
Address: 630090, Russia, Novosibirsk, ac. Lavrentyev Avenue, 6
Phone Office: (383) 330-85-70
E-mail: vorop@ict.nsc.ru
SPIN-code: 6550-0849Shokin Yuriy Ivanovich
Dr. , Academician RAS, Professor
Position: Scientific Director of the Institute
Office: Federal Research Center for Information and Computational Technologies
Address: 630090, Russia, Novosibirsk, Ac. Lavrentiev ave., 6
Phone Office: (383) 334 91 10
E-mail: shokin@ict.nsc.ru
SPIN-code: 6442-4180
Bibliography link:
Voropaeva O.F., Shokin Y.I. Numerical simulation of feedback p53 - Mdm2 in biological process of apoptosis // Computational technologies. 2012. V. 17. ¹ 6. P. 47-63
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